Neurobiology of Addiction Part 2 | Quickstart Guide
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The content segments discuss the impact of chronic stress, trauma, and addiction on the HPA axis and overall brain chemistry. It is highlighted that trauma and addiction are strongly correlated, with individuals experiencing addiction often having a higher rate of trauma. Adverse childhood experiences and chronic stress during early development can lead to physiological changes in the brain, resulting in emotional dysregulation. Compromised liver function is common in individuals with addictions, particularly those who abuse alcohol, leading to problems in neurotransmitter production and detoxification. Diabetes and addiction can also have additional complications, as uncontrolled diabetes can trigger relapse and stress the body during withdrawal and detoxification. HPA axis dysfunction is associated with hypercortisolism, which can lead to an exaggerated stress response and severe hyperarousal symptoms. Excessive cortisol and glutamate in the brain can become toxic, resulting in an exaggerated response to stimuli. Imbalances in neurotransmitters and hormones can lead to mood symptoms, cravings, and increased potential for relapse. The importance of addressing imbalances in gonadal and thyroid hormones, regulating circadian rhythms, and providing proper nutrition for hormone and neurotransmitter production is emphasized. Strategies for improving sleep quality, reducing stress, and promoting relaxation are also discussed, along with the need for a holistic approach to recovery.
The content segments discuss the impact of chronic stress, trauma, and addiction on the HPA axis and